AFC Hikari:

The World's First Vegan Tri-Peptide Formulation

for Integrated Eye & Brain Health

Beyond a Single System:

A New Paradigm in Health

The World's First Formulation for the Gut-Brain-Eye Axis

Paradigm-Shifting Science

The first vegan tri-peptide formulation engineered to target the interconnected systems of ocular and neurological health.

Scientifically Validated

Built on a foundation of five internationally recognized patents and eleven synergistic plant-derived ingredients.

Beyond Symptom Management

Designed to address the root causes of age-related visual and cognitive decline by enhancing neurogenesis, protecting retinal cells, and optimizing cerebral blood flow.

Clinically Recognized

Officially listed in MIMS (Monthly Index of Medical Specialties) as an adjuvant therapy

Engineered for Excellence:

Three Pillars of Efficacy

Five Patented Technologies

A foundation of clinically validated mechanisms for comprehensive eye and brain protection.

Three Vegan Tri-Peptides

A world-first, plant-derived peptide blend for targeted, bioavailable action.

Synergistic Botanical Extracts

An ensemble of potent antioxidants that amplify the core formula's effects.

The Five Pillars of Innovation:

A Foundation of Patented Science

Patent 1: (US20130231297A1)

Fortifying Vision & Shielding from Digital Strain

Lutein & Zeaxanthin

Form a "biological sunscreen" (Macular Pigment Optical Density) that filters harmful high-intensity blue light.

Astaxanthin

A potent antioxidant that crosses the blood-retinal barrier to neutralize reactive oxygen species (ROS) and reduce eye fatigue. It is 6,000x Stronger than Vitamin C.

Black Currant & Saffron

Improve retinal microcirculation and protect

photoreceptor cells.

Clinical trials show supplementation prevents visual acuity loss after prolonged visual display terminal (VDT) work, while placebo subjects experienced measurable vision deterioration.

Patent 2: (US9226940B2)

A Proactive Defense against Macular Degeneration

Mechanism of Protection

  • Optical Filtration: Macular pigments absorb up to 40% of damaging blue light.
  • Antioxidant Quenching: Neutralizes singlet oxygen and lipid peroxyl radicals.
  • Anti-Inflammatory Effects: Reduces cytokines (IL-6, TNF-a) that drive progression.
  • Inhibits Lipofuscin: Prevents accumulation of toxic cellular waste in retinal cells.

Patent 3: (EP2498765A1)

Cognitive Function:

The Eye's Nutrients, reimagined for the Brain

Brain Accumulation and Correlation

Lutein preferentially accumulates in key brain regions Brain Lutein concentrations directly correlate with cognitive performance.

Mechanism of Action

Protects lipid-rich neuronal membranes from peroxidation and enhances neural efficiency, enabling the brain to process information more effectively.

A 12-month randomized controlled trial showed significant improvements in complex attention, cognitive flexibility, visual learning, and visual memory compared to placebo.

Patent 4: (US10537604B2)

Natural CNS Stimulation:

Sustained Mental Energy without the Stimulant Crash

5+ Hours of Sustained Attention, Processing Speed & Reaction Time

Without increasing Heart Rate, Blood Pressure, or Anxiety

Mechanism of Action

Mangiferin (from Mango Leaf)

Acts as a non-competitive GABA-A receptor antagonist, increasing neuronal excitability without the tolerance or dependence of caffeine.

Tiger Nut Extract

Enhances neuronal glucose metabolism and mitochondrial function for sustained cellular energy.

Patent 5: (EP3538085B1)

Neurogenesis Enhancement:

Unlocking the Brain's Intrinsic Regenerative Capacity

The adult brain continuously generates new neurons

(neurogenesis) in the hippocampus, a process critical

for memory, learning, and mood.

This process declines dramatically with age and is

accelerated by modern stressors like chronic stress

and sleep deprivation.

Mechanism of Action

  • The patented interventions enhance neurogenesis by providing key nutritional factors.
  • Antioxidant protection for new neurons.
  • Reducing inflammation.
  • Increasing growth factors like BDNF.

The Vegan Tri-Peptide Core: Nature's Neurological Support System

Marigora Peptide "The Macular Shield"

Function: Delivers Lutein/ Zeaxanthin in the precise 3R,3'R stereoisomeric form that matches human macular pigment for superior uptake.

Benefit: Increases Macular Pigment Optical Density (MPOD) by 25-35%, enhancing glare tolerance and

contrast sensitivity.

Spearmint Peptide

"The Working Memory Specialist"

Function: Reduces oxidative stress in the hippocampus, the brain's working memory center. Preserves synaptic plasticity required for memory encoding. Key Stat (Visually dominant):

15% Improvement in Quality of Working Memory

Context for Stat: ...shown in a 90- day RCT in adults with age- associated memory impairment.

Mango Leaf Peptide "The Neuroprotection Powerhouse"

Function: Activates the Keap1/Nrf2 pathway, the master regulator of the body's own antioxidant

defenses. Enhances Brain-Derived Neurotrophic Factor (BDNF). Benefit: Demonstrates powerful

neuroprotective effects in Parkinson's models, preventing dopaminergic neuron death and

reducing neuroinflammation.

A Synergistic Matrix of Eight Plant-Based Powerhouses.

The effects of the core peptides are amplified by eight carefully selected berry and fruit extracts, each contributing unique polyphenols and antioxidant mechanisms.

Strawberry & Blueberry:

Cognitive protection (Fisetin) and memory enhancement (Pterostilbene, BDNF support).

Blackcurrant & Cherry:

Improved retinal blood flow (Anthocyanins) and sleep support (Melatonin).

Acerola & Lingonberry:

High-potency, natural Vitamin C and neuroprotective Proanthocyanidins.

Inulin & L-Cysteine: Prebiotic

support for the gut-brain axis and the precursor to glutathione, the body's master antioxidant.

Addressing the Full Spectrum of modern Ocular Health Challenges

Digital Eye Strain

Problem: 7-13 hours of daily screen

time leads to eye fatigue, dryness, and blurred vision from ciliary muscle fatigue and blue light stress.

Hikari's Solution: Astaxanthin protects ciliary muscle from oxidative stress while Lutein/Zeaxanthin filter damaging blue light, preventing visual acuity loss after prolonged screen use.

Age-Related Macular Degeneration (AMD)

Problem: Problem: The leading cause of

irreversible blindness, affecting 196

million people worldwide.

Hikari's Solution: Reduces progression risk by 26% through blue light filtration, direct antioxidant action, and anti-

inflammatory effects that inhibit

drivers of AMD.

Cataracts & Glaucoma

Problem: Lens opacification from

oxidative protein damage; optic nerve

damage from oxidative stress.

Hikari's Solution: Provides L-Cysteine (precursor to master antioxidant glutathione) and Vitamin C to protect lens proteins. Astaxanthin supports retinal blood flow and protects ganglion cells, offering adjunctive support for

glaucoma.

From Neuroprotection to Regeneration:

A New Defense for the Brain

Alzheimer's Disease Prevention

Addresses key risk factors by reducing

oxidative stress, modulating neuroinflammation, and supporting BDNF levels to preserve cognitive function.

Parkinson's Disease Neuroprotection

Leverages Mangiferin's effects shown in

pre-clinical models: protects dopaminergic neurons, reduces neuroinflammation, and boosts endogenous antioxidants (Glutathione ↑ 45%, SOD 160%).

Stroke Recovery & Neuroplasticity

Supports the brain's ability to reorganize.

Reduces secondary neuronal death,

enhances BDNF for circuit reorganization, and stimulates

neurogenesis to support recovery.

Proactive Neuroprotection Against Degenerative Disease

Parkinson's Disease

Mechanism: Focuses on the progressive death of dopaminergic

neurons. Mangiferin demonstrates remarkable protective effects in gold-standard preclinical models.

Key Clinical Data (from models):

Prevents dopaminergic neuron death Improves motor behavior

  • Reduces neuroinflammation (microglial activation)
  • Increases glutathione by 45% and SOD by 60%
  • Decreases ROS levels by 55%
  • Activates the GIT1/Keap1/Nrf2 protective pathway.

Alzheimer's Disease

Mechanism: Addresses key risk factors: oxidative stress, chronic neuroinflammation, and reduced Brain-Derived Neurotrophic Factor (BDNF).

Hikari's Role

Provides a multi-domain intervention by reducing oxidative load, modulating neuroinflammation, and enhancing BDNF levels to support neuronal survival and synaptic plasticity.

The Stroke Recovery Power Duo:

Hikari + SOP Subarashi Gold

The Synergy

SOP Subarashi Gold rebuilds the 'highway' (blood vessels), ensuring Hikari's neuroprotective compounds can reach and rebuild the 'city' (brain tissue).

Beyond a Single Product:

A System for Regenerative Health.

While Hikari is a powerful standalone solution for eye and brain health, its full potential is unlocked when combined with AFC's other patented formulations. Together, they create a synergistic system that addresses the root causes of chronic disease and supports whole-body regeneration.

The Ultimate AFC Trio:

Unprecedented, Comprehensive Organ Protection.

The combination of SOP Subarashi Gold, Utsukushhii, and Hikari creates a scientifically validated intervention

addressing the primary drivers of chronic disease across all major organ systems.

The AFC Trio:

A New Paradigm in Comprehensive Preventive Medicine

SOP Subarashi Gold

The Foundation for Cellular &

Vascular Regeneration.

Utsukushhii

The Core of Gut Health & Immune Optimization.

AFC Hikari

The Keystone of Eye & Brain Protection.

Together, they form a scientifically grounded approach to both preventing chronic disease and supporting recovery from established conditions.

The AFC Trio:

A Game-Changing Intervention in Health Science